Recovery Research

KPV

Name: KPV
Brand: PowerfullyPeptides
SKU: kpv
Price: 35.00 EUR
Availability: OutOfStock

KPV is a tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of α-MSH, studied for anti-inflammatory signalling in gut and immune-cell research models. Supplied lyophilised for laboratory research use only.

Read the full research profile →

How it works · what studies report · scientific references

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≥99% purity target · lot-tracked

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10 mg vial

€35.0010 mg vial

Ships from IrelandTracked

Dispatched in 1–2 working daysTracked, EU dispatch

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Currently sold out — join the Insiders list below for the restock notice.

Why does the vial look empty?

That’s normal. The peptide is supplied lyophilised (freeze-dried) — often a thin film or a few milligrams at the base of the vial, easy to mistake for empty. It’s all there; reconstitute with bacteriostatic water before use.

Research handling note

Reconstitute with bacteriostatic water and store the lyophilised vial at −20 °C until use; once reconstituted, refrigerate and use within the documented window. For laboratory research purposes only — not for human consumption, diagnostic, or therapeutic use. Need to work out your dilution? Use the reconstitution calculator →

Recovery Research

KPV — research profile

For research purposes only — not for human consumption

KPV is a tripeptide — lysine-proline-valine — corresponding to the C-terminal fragment (residues 11–13) of the hormone α-melanocyte-stimulating hormone (α-MSH). Despite its small size it retains much of α-MSH’s reported anti-inflammatory activity, which is the focus of research interest.

Research models report that KPV is taken up into cells via the PepT1 transporter and down-regulates pro-inflammatory NF-κB signalling, with particular attention to intestinal and immune-cell inflammation.

How it’s studied

PepT1 uptake: transporter-mediated entry into intestinal and immune cells.
NF-κB signalling: down-regulation of pro-inflammatory transcription.
Gut inflammation: colitis and mucosal-inflammation models.
Immune modulation: α-MSH-linked anti-inflammatory pathways.

Areas under investigation

Area	Reported research focus
Intestinal inflammation	PepT1-mediated anti-inflammatory action.
Immune signalling	NF-κB and cytokine pathways.
Skin & wound models	α-MSH-derived tissue signalling.

References

Dalmasso G, et al. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology. 2008;134(1):166–178.

Specifications

Specification	Detail
Product	KPV
Format	Lyophilised vial
Fill	10 mg per vial
Molecular formula	C16H30N4O4
Purity	Specified to a 99%+ purity target — per-batch documentation will be published once independent lab testing completes
Price	€35.00
Availability	Currently sold out — restock in progress. Join the Insiders list for the restock notice.
Supplied for	Laboratory research use only — not for human consumption, diagnostic or therapeutic use

Verifiability

Batch Testing & COA

Every production batch is sent for independent, third-party analysis at Janoshik Analytical. When results return, the full Certificate of Analysis for the exact batch you receive is published here and in our COA library, carrying its SHA-256 checksum and the lot number printed on your vial, so you can confirm the document is genuine and untampered. We publish every certificate, including any that fail.

How to verify a COA and its SHA-256 checksum →