Cellular Research

NAD+

Name: NAD+
Brand: PowerfullyPeptides
SKU: nad
Price: 70.00 EUR
Availability: InStock

Nicotinamide adenine dinucleotide (NAD⁺) is a universal redox cofactor and enzyme co-substrate central to energy metabolism (NAD⁺/NADH) and cellular signalling. Supplied lyophilised for laboratory research use only.

Read the full research profile →

How it works · what studies report · scientific references

In stock

≥99% purity target · lot-tracked

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500 mg vial

€70.00500 mg vial

Ships from IrelandTracked, inside the EU

Dispatched in 1–2 working daysTracked, EU dispatch

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Why does the vial look empty?

That’s normal. The peptide is supplied lyophilised (freeze-dried) — often a thin film or a few milligrams at the base of the vial, easy to mistake for empty. It’s all there; reconstitute with bacteriostatic water before use.

Research handling note

Reconstitute with bacteriostatic water and store the lyophilised vial at −20 °C until use; once reconstituted, refrigerate and use within the documented window. For laboratory research purposes only — not for human consumption, diagnostic, or therapeutic use. Need to work out your dilution? Use the reconstitution calculator →

Cellular Research

NAD+ — research profile

For research purposes only — not for human consumption

Nicotinamide adenine dinucleotide (NAD⁺) is a universal redox cofactor and enzyme co-substrate central to energy metabolism (NAD⁺/NADH) and cellular signalling. As a co-substrate it supports sirtuins (SIRT1–7), PARPs and CD38/CD157, which are studied in connection with mitochondrial biogenesis, DNA-repair pathways and circadian regulation.

Cellular NAD⁺ is reported in the literature to decline with age and metabolic stress through increased consumption and reduced salvage. Augmentation approaches studied in research models include precursors such as nicotinamide, NMN and NR.

How it’s studied

Redox metabolism: NAD⁺/NADH cycling in glycolysis and oxidative phosphorylation.
Sirtuins (SIRT1–7): NAD⁺-dependent deacetylases linked to metabolic and stress responses.
PARPs: DNA-repair enzymes that consume NAD⁺.
CD38/CD157: NAD⁺-consuming ectoenzymes studied in aging.

Areas under investigation

Area	Reported research focus
Mitochondrial function & ATP	Electron-transport support and ATP turnover in cellular models.
Metabolic flexibility	Insulin-sensitivity and substrate-handling pathways under metabolic stress.
Cellular & vascular aging	Sirtuin-linked pathways associated with cellular senescence.

References

Rajman L, Chwalek K, Sinclair DA. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell Metab. 2018;27(3):529–547.

Specifications

Specification	Detail
Product	NAD+
Format	Lyophilised vial
Fill	500 mg per vial
Molecular formula	C21H27N7O14P2
Purity	Specified to a 99%+ purity target — per-batch documentation will be published once independent lab testing completes
Price	€70.00
Availability	In stock — dispatched from Ireland within 1–2 working days, tracked
Supplied for	Laboratory research use only — not for human consumption, diagnostic or therapeutic use

Verifiability

Batch Testing & COA

Every production batch is sent for independent, third-party analysis at Janoshik Analytical. When results return, the full Certificate of Analysis for the exact batch you receive is published here and in our COA library, carrying its SHA-256 checksum and the lot number printed on your vial, so you can confirm the document is genuine and untampered. We publish every certificate, including any that fail.

How to verify a COA and its SHA-256 checksum →