Melanotan 1

Name: Melanotan 1
Brand: PowerfullyPeptides
SKU: melanotan-1
Price: 45.00 EUR
Availability: OutOfStock

Melanotan 1 (afamelanotide) is a synthetic analogue of α-melanocyte-stimulating hormone, studied as a selective MC1-receptor agonist in pigmentation and photoprotection research. Supplied lyophilised for laboratory research use only.

Read the full research profile →

How it works · what studies report · scientific references

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≥99% purity target · lot-tracked

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10 mg vial

€45.0010 mg vial

Ships from IrelandTracked

Dispatched in 1–2 working daysTracked, EU dispatch

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Currently sold out — join the Insiders list below for the restock notice.

Why does the vial look empty?

That’s normal. The peptide is supplied lyophilised (freeze-dried) — often a thin film or a few milligrams at the base of the vial, easy to mistake for empty. It’s all there; reconstitute with bacteriostatic water before use.

Research handling note

Reconstitute with bacteriostatic water and store the lyophilised vial at −20 °C until use; once reconstituted, refrigerate and use within the documented window. For laboratory research purposes only — not for human consumption, diagnostic, or therapeutic use. Need to work out your dilution? Use the reconstitution calculator →

Cosmetic Peptides

Melanotan 1 — research profile

For research purposes only — not for human consumption

Melanotan 1 (also known as afamelanotide) is a synthetic analogue of α-melanocyte-stimulating hormone (α-MSH). Compared with Melanotan 2 it is studied as a more selective MC1-receptor agonist, focusing its activity on the pigmentation pathway.

By activating MC1R on melanocytes it is studied for stimulation of eumelanin synthesis and for photoprotective effects; the same molecule has been developed clinically for the light-sensitivity disorder erythropoietic protoporphyria.

How it’s studied

MC1R selectivity: pigmentation-focused melanocortin signalling.
Eumelanin synthesis: melanin production in melanocyte models.
Photoprotection: UV-response and skin-protection pathways.

Areas under investigation

Area	Reported research focus
Pigmentation	MC1R-driven eumelanin synthesis.
Photoprotection	UV-response and skin-protection models.
Receptor selectivity	MC1-focused vs non-selective melanocortin activity.

References

Langendonk JG, et al. Afamelanotide for erythropoietic protoporphyria. N Engl J Med. 2015;373(1):48–59.

Specifications

Specification	Detail
Product	Melanotan 1
Format	Lyophilised vial
Fill	10 mg per vial
Molecular formula	C78H111N21O19
Purity	Specified to a 99%+ purity target — per-batch documentation will be published once independent lab testing completes
Price	€45.00
Availability	Currently sold out — restock in progress. Join the Insiders list for the restock notice.
Supplied for	Laboratory research use only — not for human consumption, diagnostic or therapeutic use

Verifiability

Batch Testing & COA

Every production batch is sent for independent, third-party analysis at Janoshik Analytical. When results return, the full Certificate of Analysis for the exact batch you receive is published here and in our COA library, carrying its SHA-256 checksum and the lot number printed on your vial, so you can confirm the document is genuine and untampered. We publish every certificate, including any that fail.

How to verify a COA and its SHA-256 checksum →