TB-500

Name: TB-500
Brand: PowerfullyPeptides
SKU: tb-500
Price: 49.00 EUR
Availability: OutOfStock

TB-500 is a synthetic peptide corresponding to the active region of thymosin β4, a naturally-occurring actin-regulating protein studied in wound-repair, angiogenesis and cell-migration research models. Supplied lyophilised for laboratory research use only.

Read the full research profile →

How it works · what studies report · scientific references

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≥99% purity target · lot-tracked

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10 mg vial

€49.0010 mg vial

Ships from IrelandTracked

Dispatched in 1–2 working daysTracked, EU dispatch

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Currently sold out — join the Insiders list below for the restock notice.

Why does the vial look empty?

That’s normal. The peptide is supplied lyophilised (freeze-dried) — often a thin film or a few milligrams at the base of the vial, easy to mistake for empty. It’s all there; reconstitute with bacteriostatic water before use.

Research handling note

Reconstitute with bacteriostatic water and store the lyophilised vial at −20 °C until use; once reconstituted, refrigerate and use within the documented window. For laboratory research purposes only — not for human consumption, diagnostic, or therapeutic use. Need to work out your dilution? Use the reconstitution calculator →

Recovery Research

TB-500 — research profile

For research purposes only — not for human consumption

TB-500 is a synthetic peptide based on the biologically active region of thymosin β4 (Tβ4), one of the most abundant actin-binding proteins in mammalian cells. It is studied for its role in regulating actin, the cytoskeletal protein central to cell structure and movement.

By sequestering actin monomers, Tβ4 is reported to influence cell migration, angiogenesis and tissue remodelling — which is why the peptide is of research interest in wound-repair and connective-tissue models.

How it’s studied

Actin sequestration: regulation of the actin monomer pool that drives cytoskeletal assembly.
Cell migration: movement of repair and endothelial cells into injured tissue.
Angiogenesis: formation of new blood vessels in wound-healing models.
Inflammation: modulation of inflammatory signalling during repair.

Areas under investigation

Area	Reported research focus
Wound repair	Cell migration and re-epithelialisation pathways.
Cardiac & muscle	Tissue-remodelling models after injury.
Angiogenesis	Endothelial-cell and vessel-formation studies.

References

Goldstein AL, Hannappel E, Kleinman HK. Thymosin β4: actin-sequestering protein moonlights to repair injured tissues. Trends Mol Med. 2005;11(9):421–429.
Malinda KM, et al. Thymosin β4 accelerates wound healing. J Invest Dermatol. 1999;113(3):364–368.

Specifications

Specification	Detail
Product	TB-500
Format	Lyophilised vial
Fill	10 mg per vial
Molecular formula	C212H350N56O78S
Purity	Specified to a 99%+ purity target — per-batch documentation will be published once independent lab testing completes
Price	€49.00
Availability	Currently sold out — restock in progress. Join the Insiders list for the restock notice.
Supplied for	Laboratory research use only — not for human consumption, diagnostic or therapeutic use

Verifiability

Batch Testing & COA

Every production batch is sent for independent, third-party analysis at Janoshik Analytical. When results return, the full Certificate of Analysis for the exact batch you receive is published here and in our COA library, carrying its SHA-256 checksum and the lot number printed on your vial, so you can confirm the document is genuine and untampered. We publish every certificate, including any that fail.

How to verify a COA and its SHA-256 checksum →